Thursday, November 10, 2011

Chronic Spinal Pain: What the Literature Says

Introduction:

For most episodes of back pain, especially when chronic, no exact pathological cause can be identified.  However, numerous clinic and scientific studies have shown that patients with low back pain do exhibit abnormal spinal motion.  This abnormal motion can be both a cause of back pain and a symptom.  For example, muscles that are strained or deconditioned can put excess stresses on the joints of the spine, producing abnormal motion.  Similarly, abonormal moving joints that can cause abnormal spinal motion can put excess stresses on the muscles and ligaments surrounding the joints.

Back pain is one of the most common neurological ailments that people suffer from all over the world.  Second to only upper respiratory infections, it is the one of the most common reasons for absenteesm from activities such as work and account for millions of dollars spent in health care costs every year.  Most cases of back pain are often self-limiting and will go away in a couple of days or so.  Other cases of back pain take much longer to resolve or lead to much more serious conditions.

Acute Lower Back Pain:

Acute back pain generally lasts from a few days to a few weeks. Most acute back pain is mechanical in nature, and the result of trauma to the lower back or a disorder such as arthritis.  Acute pain in the low back can be due to a number of things including sports injuries, work around the house, slips and falls, posture at work (either sitting or lifting), and other stressors of the spine.

Symptoms:

Symptoms may range from muscle ache to shooting or stabbing pain (due to muscle or nerve referral), limited flexibility and/or range of motion, or an inability to stand straight. Pain felt in one part of the body may radiate from a problem elsewhere in the body (for example, neck pain can cause shoulder, elbow and arm pain). Some acute pain syndromes can become more serious if left untreated. Lower back pain unrelated to trauma or other known cause is unusual in pre-teen children, although, heavy backpacks can strain the back.

Chronic Lower Back Pain:

yorkville chiropractor back painChronic back pain is measured by duration, pain that persists for more than 3 months is considered chronic. It is often progressive and the cause can be difficult to determine.  Often, in addition to the musculoskeletal complications contributing to the pain, many psychological causes can also be identified.  Being in pain for a long period of time does affect mental attitude.  The person may become depressed mental attitude due to length of having the pain, having tried various treatments that have not worked, being off work and not making money or feeling useless, not being able to do the things they enjoy like playing sports, gardening, walking, etc etc.

A study by Giles and Muller (2003) that appeared in SPINE, compared the effectiveness of 3 different common treatments of chronic low back pain, in terms of their effectiveness.

Medications:

NSAIDsPatients with chronic spinal pain that seek the care of physicians frequently report high unmet needs and expectations.  The common drugs that are prescribed for low back pain include NSAIDs (Non-steriodal anti-inflammatory drugs), which essentially just mask the problem and fail to get to the root cause of the pain. As well the adverse reactions to NSAIDs have been well documented, including:
  • Gastrointestinal toxicity, which can manifest as stomach bleeding and ulcer formation (extremely common)
  • Allergic reactions
  • There is currently insufficient evidence in the literature for the use of NSAIDs for chronic low back pain, although they may be effective for short-term symptomatic relief.  Over 6,000 people die every year from the use of over-the-counter anti-inflammatories.

Acupuncture:

medical acupunctureEvidence on acupuncture for the treatment of chronic spinal pain is growing in it's favour.  Some evidence in a meta-analysis stated that acupuncture works quite well for low back pain as well as neck pain.  The current levels of evidence of high quality randomized controlled clinical trials of acupuncture for chronic low back pain is enough to warrant its practice.  The side effects of acupuncture are very low in comparison to medical treatments.

Spinal Manipulation (SMT):

SMT has been extensively researched and shown to be effective for acute low back pain in the short-term, and has been shown to be much more favourable comparable to medical care for long-term low back pain in terms of disability.  Patients undergoing chiropractic treatments were found to be more satisfied after one month of treatment.  The SMT performed was a high-velocity low amplitude thrust to the affected joint (as determined by the examiner) to mobilize the joint.

Study Protocol:

Patients were taken from an outpatient clinic at a multi-disciplinary hospital and were assessed by a sports medicine physician to determine whether they met the criteria for this study.  They were included if they were determined to have uncomplicated (mechanical) low back pain for a minimum of 13 weeks and less than 17 years.  They did not participate in the study if they had nerve root involvement, spinal anomalies, previous surgery, spondylolisthesis greater than grade 1, and/or leg length inequality of greater than 9mm with scoliosis.

The patients were randomized to medical treatment, acupuncture, or SMT group.  In total 36 patients were allocated to each of the treatment groups. Appointments were 20 minutes in length 2x per week for up to 3 months.  NSAIDs prescribed were Celebrex, Vioxx, or paracetamol.  Improvements were measued using disability questionaires, visual analog scale, pain frequency (1- no pain to 6-constant pain), cervical and lumbar spine range of motion (ROM), and straight leg raise (SLR).

Results:


Manipulation
Acupuncture
Medication
Asymptomatic Patients at 9 weeks
9
3
2
Outcome Measures
Initial
Final
Initial
Final
Initial
Final
VAS Back
6
3
6
7
5
5
VAS Neck
6
5
6
4
5
6
Oswestry (back pain questionaire)
22
14
30
26
32
32
NDI (neck questionaire)
28
22
37
30
47
42
Lumbar Sitting flexion
50
39
49
47
54
51
Lumbar Standing flexion
40
30
54
56
56
52
Cervical sitting flexion
40
40
30
40
32
38
Cervical sitting extension
40
42
32
40
40
35
Disability questionaire
54
68
47
49
41
49

SMT yielded the best results by far over all of the outcome measures, with the exception of the NDI in which acupuncture was shown to have better results over manipulation.  Medication had the worst outcome measure of all 3 treatments. 9 patients with chronic spinal pain became ASYMPTOMATC.  The current study had rigorous protocols and a wide range of outcome measures, in which the 3 treatment regimes acted as controls for the others.  Any likely placebo effect would like be distributed across all of the 3 treatments.  SMT was, by far, the superior treatment for cases of chronic spinal pain, with every fourth patient being ASYPTOMATIC.  Acupuncture was found to be a little more effective for neck pain and disability.  The medical treatments caused adverse reactions in 6.1% of patients, that disappeared once the medication was stopped.  One final important note, is that since these patients all had CHRONIC spinal pain it is very unlikely that they would have improved by 'natural history' or 'self-limiting' improvements.

Reference:

Gilles, S., and Muller, R. 2003. Chronic Spinal Pain: A Randomized Controlled Trial Comparing Medication, Acupuncture, and Spinal Manipulation. SPINE, Volume 28(14): 1490-1503

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